ON Prime2 Adelaide teams

Table 1: Adelaide teams
Team Name Lead Institute Sci-tech proposition

Biological Joint Robotic-Testing System

University of Adelaide

The movement of our joints is very complex; because of this, joint implants often fail and need to be recalled. Our team has developed a six-degree-of-freedom (6DOF) robotic testing system to accurately simulate and improve fundamental understanding of physiological joint motions, which can be used to rigorously test new implant designs. Our testing solution is more cost-effective and functionally capable than existing 6DOF solutions on the market thanks to the unique robot structural design, consistent updates of the robot software (e.g. comprehensive test protocols and automated test programs), and 6DOF load control at real-time speeds (currently under development).

Breakthrough Antiviral DNA Vaccines

CSIRO Health and Biosecurity

Injectable vaccines are expensive and difficult to deliver in resource poor nations. This is due to the need for cold chain storage and technical staff for vaccine administration. Our team is addressing the need for temperature-stable needleless vaccines by developing cost effective and efficient inhalable vaccines.

D-START, Neil Kirby

University of Adelaide

We have developed a computerised Disability support needs assessment program (D-START) in association with the State Governent of South Australia. We also have a computerised Secondary School student support needs assessment program (START) designed to assess student issues related to completing school and transitioning to post school options. D-START has the capacity to improve the effective and efficient delivery of disability and aged care services, and START can provide secondary schools and the associated student counsellors with important information about students issues that can be used to facilitate successful completion of secondary school and transitioning to worthwhile post school options.

DCP - Improved care for people attending general practices

University of Adelaide

Prevention is better than cure. However, Australians are receiving only half of the recommended preventive care despite seeing their general practitioner an average of six times each year. Patients and general practitioners remain unaware that fundamental elements of care have not been offered or provided. People don’t know what preventive care is recommended for them, or whether any of that care is due to be performed. They want and expect their general practitioners to tell them. Our technology helps people to receive recommended preventive care from their general practitioner with a minimum of time, effort or cost.

In home test for chemotherapy-induced diarrhoea

University of Adelaide

Chemotherapy for cancer causes debilitating and unpredictable diarrhoea. We are developing an in-home test to help patients track changes in their gut bacteria during chemotherapy, and predict the onset of diarrhoea. This will provide patients with greater control over their cancer treatment and valuable information about the likelihood and onset of diarrhoea. Ultimately, this test will ensure optimal management of diarrhoea via the proactive delivery of supportive care measures thus improving the quality of life for cancer patients and the likelihood of remission.

Increased Intestinal Permeability - Leaky Gut Test and Diet

CSIRO Health and Biosecurity

Our proposition is to provide consumers with a more convenient, faster and cheaper blood test for the diagnosis of increased intestinal permeability or leaky gut, which is associated with some debilitating gut symptoms such as abdominal pain, bloating, diarrhoea, loud bowel sounds, flatulence, indigestion and constipation. In addition we will provide a simple dietary plan for consumers to follow to restore and maintain the gut for improved health and wellbeing. These services will be available at a convenient location such as a local health clinic or a diagnostic or a pathology laboratory.

MicroPoll

CSIRO Land and Water

Micropollutants are chemicals found in the environment that can, at very low levels, threaten the health of organisms and ecosystems. Detecting these chemicals and predicting their toxicity presents a challenge to government, industry and public utilities. Our micropollutant screening tools will help environmental testing laboratories who want to advise on potential micropollutant risk by providing early and accurate detection of emerging contaminants, enabling near real-time management decision-making and solutions.

Portable Hardware Energy Optimisation (PHEO)

University of Adelaide

Many smartphone users routinely complain about inadequate battery life. One way to increase energy efficiency is to configure devices and apps according to usage patterns. However, the involved software development processes are expensive, labour-intensive, and error prone. PHEO's aim is to put methods from the area of computational intelligence at the core of software engineering processes. The resulting next-generation software products will dynamically adapt themselves: they analyse their collected usage data, perform what-if analyses, and optimise their configurations accordingly for the next usage period. Hence, the products will be faster, more reliable, and less energy-hungry.

Flinders FPEP

Flinders University

Defence personnel are often deployed at short notice to locations that are very different to their usual living and training environment. With limited time to acclimatise to new environmental conditions, physical and mental performance may be sub-optimal and tasks can be compromised. This is a problem not only for individual defence personnel but also the potential effective functioning of units. It is therefore vital to understand the particular requirements and susceptibilities of individuals moving at short notice to locations that are very different to their usual living and training environment. Based on this, we can provide tailored preparation and support to maximize their ability to operate at top end of their capacity to mitigate physical and mental stress.

LASAGNE Applications

Defence Science and Technology Organisation

In today's interconnected world, up-to-date operational data is invaluable for organisations to support critical decision making. With the advent of the Internet of Things and Big Data, an organisation’s potential to quickly analyse operational data is unparalleled, however, connecting heterogeneous data sources still presents a significant challenge. Have you ever wondered how to connect multiple dispersed computer systems? Ever come across barriers prohibiting the flow of information being disseminated in your organisation? LASAGNE is a software framework that can be applied to these problems, aiding the free flow of data in a network and accelerating your ability to make decisions.

Rapid detection of insect traits using near-infrared spectroscopy

University of Queensland

The mosquito Aedes aegypti is the principal vector for all four dengue virus serotypes, as well as Zika and chikungunya viruses. Current methods of arbovirus detection in mosquitoes involve tedious and time-consuming detection of viral RNA through quantitative reverse transcription polymerase chain reaction (RT-qPCR). it is expensinve, and normally means that testing is only conducted on small, inadequate samples. Near infrared spectroscopy (NIRS) is a non-destructive technique of measuring the radiated energy reflected from biological samples following their partial penetration by an electromagnetic beam. NIRS can detect multiple parameters simultaneously (including mosquito age, arbovirus infection, and Wolbachia infection), is portable, simple to use, and can be used in areas with minimal infrastructure. It will considerably improve the speed, accuracy and capacity of arbovirus evaluations and risk mapping exercises.

The SPAD Lads - SPAD based Laser Airborne Depth Sounder (LADS) System

Defence Science and Technology Organisation

LADS systems are designed to perform hydrographic surveying of shallow coastal and inland water areas, a powerful tool to determine the seafloor depth for topographical data, water column charaterisation for oil and gas detection, biomass assessments, and target detection for military purposes. Current LADS systems operate on aircraft and need a laser with sufficient power to penetrate into the water, the biggest limitation is being able to detect the weak return signal. The Single Photon Avalanche Diode (SPAD) is a type of solid-state photo-detector that is designed and biased in such a way that it has the ability to detect a single photon. Creating a collection of SPADs (or array) is possible by miniaturizing SPAD devices so that they all can fit onto a single integrated circuit chip.

Vulnerability assessment using computational material science and machine learning

Australian Nuclear Science & Technology Organisation

Determining the effects of explosive loading in different environments is a dynamically complex but essential activity in the evaluation of structural vulnerability of protective armour and the minimization of blast-induced damage susceptibility. Our existing methods of determining and assessing material vulnerability are computationally expensive requiring complex modelling of structural responses and involve large data sets. Our solution is to develop, in parallel, a machine learning software tool which can make rapid vulnerability assessment against multifactorial explosive loading, environmental and material data. This will build on experimental tests, modelling and simulations and literature sourced data to train the algorithms.

ON Prime2 Brisbane teams

Table 2: Brisbane teams
Team Name Lead Institute Sci-tech proposition

A simple, reliable and accurate test for detection of gluten-containing cereals

CSIRO Agriculture

Coeliac disease affects 1% of the global population and the only treatment is a lifelong gluten-free diet. Accurately detecting gluten contamination in GF products is critical to consumers and manufacturers as it poses a risk to the consumer (health) and to the manufacturer (recalls, loss of income, reputation). Current testing using antibodies is inaccurate. We will develop a simple accurate and reliable test allowing detection and accurate quantification of trace levels of these potentially-toxic cereals in both raw and processed foods providing assurance to consumers and manufacturers alike.

All-in-one shrimp (prawn) pathogen detection system, Melony Sellars

CSIRO Agriculture

Pathogens in global prawn aquaculture cause economic losses of $18B annually. Current detection methods cost $40-80 per sample/animal to detect one type of pathogen, with prawns often harbouring multiple pathogens simultaneously, and detection methods having slow turnaround times. The costs and lack of timeliness means current screening of key pathogens is used sparingly by seedstock producers and research agencies, and not at all by commercial farms. The all-in-one pathogen detection system will allow commercial farming sectors to screen 13 commercially relevant pathogens in a cost-effective and timely manner, enabling data-driven transformation of production yields through better management of prawn stocks.

AvoCulture

University of Queensland

With the current Aussie avocado market trading volumes worth $770m/year and an explosive global demand that just keeps growing; Aussie Avocado farmers are under so much pressure to produce more they are now paying a record $50 per tree! The major bottleneck is undersupply of new planting material. This is caused by lack of a cost-effective and efficient technology for avocado plant propagation. We present a new, high-throughput, cost-effective propagation technology, free from environmental and seasonal constraints, to capitalise on the booming opportunity for avocado market expansion in Australia and globally.

BLEAT

Data61 CSIRO

For many applications, real-time sub level location accuracy is needed within complex environments such as shopping complexes, buildings, work places etc. While many solutions already exist, from video (image processing), AGPS, Wi-Fi and Bluetooth based solutions, through to bespoke hardware/software tracking technologies, there is a need for a low cost, scalable solution that can accurately allow items (people, assets, etc.) to localise themselves in real-time within complex work environments. The BLEAT system allows clients to easily deploy and maintain the beacon network and achieve real-time localisation of people and assets using smartphones and low cost, off-the-shelf devices for asset tracking.

Quantitative Radiology Reporting for Alzheimer’s Assessment

CSIRO health and biosecurity

Alzheimer’s disease (AD) is characterized by a progressive and gradual decline in cognitive function. Recent advances in Positron Emission Tomography (PET) has allowed two hallmarks (Amyloid and Tau proteins) of AD to be measured many years before clinical symptoms. In collaboration with world leading clinicians (Prof Rowe and Villemagne), the CSIRO has developed software to extract the specific information implicated in AD. This is provided as a clinical report with quantitative and qualitative assessment. These measures will allow improved diagnosis and allow the doctor and patient to better understand the implications of their diagnosis, its certainty, and plan appropriately.

Working Well

University of Southern Queensland

Stress and burnout are significant problems for healthcare workers, and result in adverse outcomes for practitioners, patients, and organisations. In fact, stress and burnout among healthcare workers has been associated with increased risk of making medical errors, higher rates of absenteeism and staff turnover, poorer interactions with patients, and greater risk of the practitioner experiencing further emotional difficulties, such as anxiety or depression. Our team, Working Well, is committed to using innovative methods to improve the health of our health practitioners, which in turn leads to healthier communities for Australians.

ON Prime2 Canberra teams

Table 3: Canberra teams
Team Name Lead Institute Sci-tech proposition

Buzz Balance Ball

University of Canberra

Balance and body awareness are typically taken for granted by much of the population. However, compromises in these sense can have significant impacts on sufferers - approximately 30% of adults of the age of 65 or older are affected by poor balance. The Buzz Ball combats these. Rather than simply using exercises, the Buzz Ball adds a new dimension of spatial information through touch receptors in the hands. By doing this, it can fine-tune the other senses contributing to balance for increased accuracy and performance. Not only does the Buzz Ball enable the user to retrain their senses to maintain or regain their indepecnce, it can be done from the privacy and comfort of a users home, removing the potential for embarassment. The buzz ball is simple to use, requiring no user training and low cost.

Conservation connect

CSIRO Land and Water

Australia spends hundreds of millions of dollars each year on conservation, yet our unique biodiversity is still in decline. There is a huge opportunity in the biodiversity conservation world to use scientific and digital progress for better outcomes for people and nature. Our digital platform CONSERVATION CONNECT will connect conservation managers with conservation funders using smart matching technology. CONSERVATION CONNECT will harness and create the best available information on current, most-needed and most cost-effective management actions to solve Australia’s biodiversity crisis.

Delta Core

RMIT

Delta Core falls into the category of Serious Games and is the gamification of the first stage of forensic fingerprint analysis. Players examine real casework prints, analysing them in the same way forensic experts do by spotting and marking features in the ridge pattern. If successful, players unlock access to higher difficulty prints, cold case files and potentially live casework. Delta Core is designed to identify members of the public with a high affinity for fingerprint analysis and this will reduce the time taken to train new experts where such players can be recruited by law enforcement agencies.

Fluid Telemetry

University of Canberra

Errors in Intra Venous (IV) fluid intake measurements have serious negative consequences for patients, one of which is fluid overload (hypervolemia). Current methods used by nurses and doctors to measure, monitor and record IV fluid administration rely heavily on manual input of information by nursing staff, and are error prone. “IV Fluid Telemetry” is a novel, IoT based system that accurately measures and records cumulative IV fluid intake in hospitalized patients. It is more accurate than current methods, and compatible with existing IV fluid administration products in the market. This allows for easy and cost-effective implementation in hospitals.

Macquarie Waveguides

Macquarie University

We are building better WiFi systems to change the home internet once and for all. Earlier, we looked for the modem; now the modem will look out for us. We believe that for home WiFi to be truly efficient, it should focus upon its users rather than cast broad radiation over the whole home. We have developed a system for WiFi to concentrate and focus its reach to very specific areas, perfect for use in home and for more precise WiFi use on aircraft.

Optimus

CSIRO astronomy and space science

OPTIMUS (Observing with Parkes, Training and Introduction, Module for University Science) is a package providing undergraduate students a hands-on introduction to radio astronomy observational techniques and data analysis using pulsars as the context. Offered on a subscription basis to universities globally it includes background educational material, tutorials, a virtual machine to allow students to install a complete package of relevant software tools, access to data and a number of hours of telescope time on the 64m Parkes radio telescope plus support and observer training. Topics include pulsar timing and the search for gravitational waves.

Reducing noise in personal spaces

Australian National University

The majority of PhD graduates leave academia on completion of their degree, but find job searching difficult. This is because employers do not understand what PhD graduates have to offer and rarely mention the PhD as a qualification. Our prototype ‘Jobs Explorer’ website uses Natural language machine learning processing to ‘read’ large data sets of job ad texts and sort according to level of research skill required. This tool can help graduates and employers find each other and be used strategically by universities and governments who are interested in making more effective use of Australia’s annual investment in research training.

Tracking Trends

Australian National University

ON Prime2 Melbourne teams

Table 4: Melbourne teams
Team Name Lead Institute Sci-tech proposition

Caetra

Monash University

40-80% of chemotherapy patients get oral mucositis - an extremely painful ulceration of the mouth lining. Patients with aggressive tumors and receiving strong and high doses of chemotherapeutic agents like fluorouracil and cisplatin have a 90% incidence of oral mucositis. Of those that develop lesions, 11% have to discontinue or alter their chemotherapy treatment plan due to severe mucositis. Caetra is a thermally regulated oral device that can prevent oral mucositis when used simultaneously with chemotherapy infusion. Caetra protects the mouth lining from the full brunt of chemotherapy damage by reducing the tissue's metabolic rate and chemo uptake. Oral mucositis increases cost of care by $2500 - giving the Caetra device a positive cost-benefit ratio to support Medicare and private insurance coverage.

DiagamiRs - Early detection of infectious diseases

CSIRO Health and Biosecurity

Infectious diseases threaten human, animal and environmental health on a global scale. Unfortunately, many infectious diseases cannot be detected during the early stages of infection. During this time, the pathogen replicates and spreads within the host but does not manifest sufficiently to be detected using existing technologies. Our solution is a diagnostic assay that measures host responses to infection. During early stage disease, the host is rapidly mounting an exquisitely sensitive and specific immune response. Host biomarkers may inform the development of improved diagnostic assays that report disease sooner and improve infectious disease management.

New Antimicrobial Additives

Monash University

Antimicrobial resistance has been declared a global crisis. Silver is commonly used to prevent bacterial growth. However, the predominance of silver in broad-spectrum antimicrobials is causing concern due to toxicity, environmental accumulation and the emergence of antimicrobial resistance. New and safer antimicrobial additives are required, to replace silver. Our team has developed novel metal complexes showing antibacterial activity comparable to commercial silver additives, against a range of bacteria. The compounds are viable candidates for the development of new, safe antibacterial polymer-based products such as plastics and natural fibres, including coatings and packaging for clinical or community settings.

OLED Device for Home Treatment of Jaundice in Newborn Infants

CSIRO Manufacturing

Portable Phototherapy Device for Home Treatment of Jaundice in Newborn Infants: effective and safe at-home phototherapy care for newborn infants with jaundice, to reduce the requirement for hospital treatment of low risk infants. The device would comprise a battery-operated light source and power supply in a single unit, significantly smaller, more portable and safer than equipment currently available. This offers a practical and less invasive home treatment option for an essentially routine condition. Benefits include improved bonding opportunities between parents and newborns at home and reduced hospital costs.

Powering the future with printed solar films

CSIRO Manufacturing

Our growing commitment to renewable energy has seen an increasing number of solar panels spanning the rooftops of suburbia. However, conventional solar panels, based on rigid silicon, are essentially one-size-fits-all. We’re developing a flexible, lightweight, low-cost alternative to silicon in which ‘solar inks’ are printed onto polymer films. This means that clean, renewable energy can be harvested from windows, lightweight building structures and packaging, for portable devices and in remote locations and the developing world. Moreover, the design freedom of printing unlocks endless aesthetic possibilities. Printed solar – solar energy from everywhere, for everyone.

TRR Project - Remote Casualty Care Support

Monash University

The Resus Logic project aims to combine hands-free, fully auditable, secure and distributed, real-time 'wireless computer assisted decision support' with 'remote expert decision support' for pre-hospital medical care. Once achieved the Remote TRR© System will become the ‘gold standard’ for resuscitation oversight. The ON Prime Program will allow engagement with a blockchain developer and a big data analytics database developer to create a decentralised machine-learning solution for the decision-support algorithms - in response to their use, timing, efficacy and individual operator log-on. This expertise will significantly accelerate development of machine-learning algorithms for life-saving intervention in prolonged field care.

URCHIN

CSIRO Manufacturing

Biological molecules are now ubiquitous in consumer products including home care products (e.g. washing powders), biosensors, pharmaceuticals and nutraceuticals (e.g. probiotics). These molecules are susceptible to degradation over time and lose their potency if exposed to excess heat, moisture or temperature. At CSIRO we have recently developed and patented a rapid, versatile and unique method for encapsulating, protecting and preserving a range of biomolecules. Our solution is to shield the biomolecule in a resilient porous cage – a Metal-Organic Framework (MOF).

Yield Prophet

CSIRO Agriculture

Australia’s climate is one of the most variable in the world. Knowing what inputs will maximize profit is incredibly challenging for our farmers. Without a reliable guide to likely crop performance, over- or under-investment in inputs like fertiliser represents a high level of financial risk in an industry that typically operates on very tight margins. Yield Prophet is a web-based crop monitoring and forecasting tool based on highly-advanced agricultural systems modelling. It provides farmers with user-friendly guidance around yield potential and management options, and represents a valuable source of objective analysis to anchor a more profitable decision making process.

Adaptive Design Social Enterprise

Swinburne University of Technology

For individuals and their families living with a disability, assistive products have significant benefits in everyday life. Yet, these items are often highly bespoke, making them costly to produce and buy. Our solution will develop low-cost/high-design assistive products using leading-edge production and design processes, within a social enterprise business model. Using co-design processes, individuals, families and health professionals will work with designers to understand specific needs. Designers will use CAD and 3D printing to create products based on individual requirements. The social enterprise will be based at Swinburne University Technology, accessing world-leading manufacturing, design, occupational health and social enterprise expertise.

Anidra

Federation University Australia

A continuous early intervention would minimise many fatal situations in hospitals. Our Sensor Kit enables hospitals to collect and perform health score calculations automatically every minute rather than performing it manually every few hours. This results in better care, as one can detect patient health deterioration with reduced labour costs. Our product includes hardware and pre-configured software, specially written to transmit data to hospital servers or the Cloud where our algorithms process the data and make it visible to authorised healthcare workers via their mobile devices. Our product is also capable of sending alert messages to healthcare workers for early intervention.

FinTech@Deakin

Deakin University

Financial planners face a variety of challenges to obtain accurate forecasts, owing to lack of a useful tool, inconsistent approaches, and no common set of assumptions. We develop an effective financial forecasting tool that integrates both quantitative and qualitative aspects of a forecast using statistical and artificial intelligence methodologies. This software product aims to provide forecasts based on quantitative analysis from data and qualitative knowledge from domain experts to account for business variations and market predictions. With the increasing magnitude of financial transactions, the proposed tool will play an important role in supporting financial planners in their decision making processes.

Pharmacy Simulator

University of Tasmania

A simulation tool that allows students to practice professional duties in an immersive and engaging virtual environment. Our technology enables the rapid implementation and distribution of 3D computer-based simulated learning experiences that are dynamic, expressive, and impactful. Prior solutions lack user-driven content creation and customisation features, making them difficult to embed into your curriculum. Our solution allows educators to create or modify training scenarios to suit their particular teaching needs. Scenarios are shared through the cloud, benefitting the broader community and ensuring that there is a continually expanding suite of content for students to experience.

Smarter Irrigation

University of Tasmania

Agriculture is the biggest user of water supply in Australia. Farmers need to make more accurate, timely and spatially cognisant irrigation management decisions. However current irrigation practices are often inefficient or ineffective in part due to the poor adoption of irrigation scheduling devices. We have developed software to enable growers to identify different soil types, and guide growers as to how much water to apply to each soil zone depending on their crop and local weather forecasts. Information is displayed as simple colour coded map of the irrigation area via a mobile phone.

StableMate

La Trobe University

The global uptake of smartphones means that most of us also have a high-resolution camera in our pockets. Using smartphones to accurately record images has pervaded all aspects of our lives, including in research and education. The microscopic world is one area where recording images is tricky with a smartphone. We have developed an interface that connects the smart phone to a microscope, ensuring easy capture of quality images (stills or video) delivered into the hands of the user. The added benefit is in simplifying administrative processes around data collection and image sharing between users.

Ultrasound for more seed oil recovery

CSIRO Agriculture

CSIRO has developed the megasonics technology for increased oil recovery from oil processing by-product or co-product materials. It consists of pretreating the oil bearing material with sound waves to further separate and remove the oil in oil extraction processes. The ON Program will help understanding the product-market fit and refine the value proposition for megasonics, which has proven potential for sustainably reducing the oil losses in cake to about 30-50%. The implementation of the megasonics technology in the seed oil processes will unlock opportunities for annual recovery of oil projected to be of $17M in Australia and $2.2B globally.

ON Prime2 Newcastle teams

Table 5: Newcastle teams
Team Name Lead Institute Sci-tech proposition

Affie: an emotional thesaurus

University of Technology Sydney

You’ve heard of a thesaurus – it identifies words with similar literal meanings. We have an idea for an emotional thesaurus. It draws on scientific data to identify words that feel similar to other concepts. It’s a data-driven tool for thinking outside the literal box. Affie suggests Mac computers feel like playmate, dance with and young. Conversely Windows computers feel like school teacher, talk to and cooperative. Affie provides innovators a way of exploring the emotional core of an issue to better connect with the deeper needs of users. With affect and emotion gaining prominence in innovation, Affie aims to promote ideas that make sense emotionally and socially, as well as economically.

Amino Acid Biotechnology

University of Newcastle

Current detection methods cost $40-80 per sample/animal to detect one type of pathogen, with prawns often harbouring multiple pathogens simultaneously, and detection methods having slow turnaround times.

Better CO2 capture by design

CSIRO Energy

There is a growing demand in industry for effective carbon dioxide (CO2) removal technologies. Many gas resources contain CO2 which needs to be removed before transport or use. With growing concerns around climate change CO2 removal from exhaust gases represents a significant emerging market. The removal of CO2 comes at large costs as the standard process using absorption liquids requires significant amounts of energy. We have developed a range of bespoke absorption liquids that can absorb more CO2 than the standard solutions and release it at lower energy requirement. Our aim is to identify suitable commercialisation pathways for this technology.

Health Technology Evaluation

University of Newcastle

We evaluate the evidence behind health technology claims. Healthtech startups are being launched at a rapid pace, some of the technology works, some of it harms. Unfortunately the framework and methods for assessment are lagging behind development and adoption. Users have been subjected to poorly validated technology and investors have lost millions of dollars. Our service will bring state of the art clinical, epidemiological, public health, cyber security and health economic analyses together with digital monitoring of patient outcomes to protect patients, health care organisations, insurers, and healthtech investors. Rigorous evaluation and monitoring ensures the product is safe, clinically effective, and cost-effective.

Hyperdrive

Macquarie University

Locating drug proteins is essential for good drug design and to better understand the processes and side effects of drugs. Current methods used to locate these proteins are time consuming and labour intensive. We will streamline this process by identifying the proteins of small molecules that are destined for pharmaceutical or agrichemical uses via a combination of chemical synthesis and protein display technologies.

Low cost carbon fibres from coal

University of Newcastle

A global race is now on to develop low cost carbon fibres to meet the growing demand in the automotive and renewable energy sectors. A step change in carbon fibre cost will allow deeper adoption into a wide range of technologies, for example reducing vehicle weight and emissions. As a feed material, coal is 50-100 times cheaper than current precursors. Coupled with an innovative processing technology, this project could transform Australia (and in particular the Hunter Valley) from a global supplier of coal to a leader in advanced manufacturing of carbon composites.

VR Rehab

University of Newcastle

The lives of stroke patients and brain trauma survivors change dramatically after their stroke, often leaving them with physical and cognitive impairments, depression, anxiety, and lack of social support. Our solution is the creation of a virtual reality (VR) enviroment that delivers gamified interventions for improving a stroke patient's connection to him- or herself. This would be accomplished by patients using home-accessible VR equipment that is set up for regimented or leisurely use in manner that cultivates interest and usage. The goal is to not only 'recover' lost function, but to offer a pathway to renewal of self.

ON Prime2 Perth teams

Table 6: Perth teams
Team Name Lead Institute Sci-tech proposition

ABCEASE

University of Western Australia

The Abcease device is an innovative, novel medical device for clinical management of complex subcutaneous abscesses. Developed by a team of clinicians, engineers, scientists and management consultants, the Abcease device system provides both initial incision and drainage, as well as ongoing management of the abscess contents during healing. Abcease stands to shift the treatment of deep subcutaneous abscesses from an in-patient procedure requiring general anesthesia to an emergency department procedure. This will improve patient safety, and reduce costs to the patient and healthcare system. Abcease has freedom to operate, and is protected with an Australian provisional patent.

APC for Sustainable Planet

Curtin University

Ordinary Portland Cement (OPC), which is one of the most widely used construction materials, is associated with many problems related to the sustainability of the planet. A more sustainable alternative cement called Alkali Pozzolan Cement (APC) has been developed at the laboratory of Curtin University to resolve this problem. The team seek the opportunity to manufacture APC commercially through an industrial partner(s). The potential customers are the constructors of concrete/masonry structures who use OPC.

FFR Project

Curtin University

Surgeons who perform multi-level spinal surgery use rods to hold the unstable spine together and initiate fusion of the joints or fracture. However the spine is not straight and each spine is different and so these rods need to be bent in multiple locations to fit the profile of the screws that are attached to the spine. Bending of fusion rods to fit polyaxial screws is onerous, time-consuming and impractical to do perfectly for multilevel fusions and can significantly increase surgery time. To address these problems we have developed a rod that is initially flexible and can be easily manipulated by the surgeon’s hand during the operation to suit the required rod trajectory. After insertion of the rod in the body, the screw heads are tightened and then, once the rod is in place and exactly the right shape, it is rigidified.

Inflamark-A

University of Western Australia

Currently we lack a cheap and reliable method to assess how well specific anti-inflammatory treatments work for individual patients, or to quickly assess clinical efficacy of new drugs developed to target inflammation. Integral to inflammatory processes are neutrophils, a type of immune cell, which secrete damaging molecules upon activation. We have identified a uniquely modified protein biomarker of neutrophil activation which can be measured in blood from a painless and easy to perform fingerpick sample. The biomarker will be packaged into a kit targeted at research institutions where positive feedback will pave the way for introduction into clinical settings.

Injury Alarm

Edith Cowan University

In Australian and all industrialised nations' workplaces there is an unacceptable frequency and cost of serious injuries. 'Injury Alarm' provides a mechanism to identify the level of risk in an organisation, defines what it must to in response to the level of risk including ensuring effective emergency management. The solution analyses existing safety data and information, so organisations do not need to implement a new program as part of this process. This product enables organisations to be proactive, like an alarm warns of danger, to forecast injuries and therefore be proactive, rather than prevent recurrence.

Power Transformer

Curtin University

Frequency Response Analysis (FRA) is a powerful diagnostic technique that is widely known as the only reliable tool to detect mechanical deformation within power transformers. To conduct the test, the transformer has to be taken out of service which may cause interruption to the electricity grid. Moreover, because FRA relies on graphical analysis, it calls for expert personnel to conduct the test and to analyse its results, as so far, there is no published reliable standard code for FRA interpretation worldwide. This research team is aimed at proposing an alternative technique to automatically identify power transformer winding deformation in real time.

PROhealth APP

Murdoch University

Quality of life is often affected in chronic disease, but is not considered systematically in clinical care because assessment is largely paper-based and generates unwieldy data. The PROhealth APP delivers electronic patient self-reports from personal devices into medical practice through a secure portal. Using a custom interface, doctors review a pre-processed synthesis of the reports with patients during their visit. Patients benefit by having their psychosocial needs met and doctor’s capacity to deliver holistic care will increase. The product supports longitudinal data collection and is configurable to enable use in diverse health care contexts.

The Amber System

University of Western Australia

Ventilator Associated Pneumonia (VAP) is the most common hospital acquired chest infection that occurs in the intensive care unit (ICU).  VAP doubles patient mortality rates, contributes to half of all antibiotic use in ICU, and costs the US health care system up to $5.1 billion USD annually.  When a patient is intubated, the endotracheal tube used provides a direct conduit from the mouth for bacteria to enter into the lower respiratory tract – a perfect breeding ground for infection. Our AMBER System is a unique endotracheal tube device that seeks to lower the incidence of VAP in ICU patients by inhibiting bacterial biofilm growth within the tube, in a safe manner that does not depend on antibiotic use.

ON Prime2 Sydney teams

Table 7: Sydney teams
Team Name Lead Institute Sci-tech proposition

3DC Analytics

University of Wollongong

Over 10% of the worldwide adult population suffers from debilitating brain diseases. The impairments are often life-long, with substantial impact on the quality of life. While billions have been spend developing drugs against a range of brain disorders, their benefits are limited and often come at the cost of severe side effects. This dire situation is largely caused by a lack of reliable, cost-effective and scalable human brain models of these diseases. 3DC Analytics is developing the capacity to improve the identification and selection of beneficial drug candidates against brain disorders and stop ineffective treatments early in development before major resources are spend.

HipSafe

University of Wollongong

Worldwide, annually 1.6 million hip fractures occur and by 2050 it is expected to reach 6.3 million. This problem particularly affects elderly people (over the age of 50) and those living in long term care facilities. In Australia there are 20,000 hip fractures from falling per year and it is increasing by 40% each decade. Issues with existing hip protectors include usability for users and staff in Long Term Care facilities. They provide major obstacle for the elderly when engaging in daily activities. Our improved solution will provide appropriate protection and superior usability, therefore increasing patient adherence to hip protectors.

Nanosensors for environmental monitoring

CSIRO Manufacturing

Environmental pollutant analysis, monitoring and reporting currently involves a number of costly and time-consuming steps, which are crying out for a disruptive technology solution. In line with this, we have a novel, portable sensing technology that can detect organic environmental pollutants at a fraction of the cost of current methods. This technology can be adapted to in-field analysis, remote sensing, and even the formation of integrated smart sensor networks for real-time feedback of environmental systems. We envisage this technology disrupting enterprises within mining and chemical processing, in addition to assisting environmental regulatory agencies.

OurFlora

University of Sydney

Botanical knowledge is critical for monitoring and mitigating the effects of climate change, shoring up food security and for developing cultural competence in our community. What if, with each passing generation as a community we knew less and less about plants? Despite most of us knowing that plants photosynthesise and produce oxygen for us to breath, we seem to know little else. OurFlora offers a collaborative way to learn botanical and cultural narratives of the street trees in your suburb, and for school children to learn aboriginal words from stories that have been connected to the land for thousands of year. OurFlora.  Our solution.

Pedestal

Macquarie University

The web platform Pedestal (currently in beta form) helps educators and learners in a wide range of disciplines and levels who want to utilise 3d object models in online learning. It does this by lowering the technology limitations of traditional offline methods to view 3d and enhance the learning experience through new and novel approaches to object based learning.

Real-World Optimization Platform

Macquarie University

In the modern world, engineering analysis and design rely heavily on computer-aided engineering software. A key component of such software systems is efficient global optimization algorithms for solving complex design problems. Yet even the most advanced commercial multidisciplinary design packages are struggling to provide a solution when it comes to optimizing real-world design parameters. Without this capability, optimized designs still need additional manual refinements, which prolong the design cycle and increase the cost of a product. By using our optimization platform, our clients (technology companies, engineers, R&D companies, researchers, etc.) will be able to progress rapidly and confidently from an idea to its implementation.

Smart Antennae Systems

Macquarie University

A low-cost, power efficient and compact beam-steering antenna system is pivotal in providing satellite based high-speed internet services.

Current mechanical beam-steering technologies are bulky and expensive. Alternative electronic methods are inefficient and also expensive. Our invention fills a large gap between existing mechanical and electronic beam-steering methods by providing high performance in a small package at low cost.

Vibrant Data

University of Technology Sydney

Vibrant Data wants to maximise agricultural crop production by optimising irrigation and fertilisers in the field. Using a large network of wireless sensors in agriculture fields, Vibrant Data can measure the humidity of the soil; additionally, the integration of precipitation live feeds helps manage irrigation. The sensors will measure a range of dimensions, including but not limited to pH and temperature. With this data, soil nutrient levels will be far more accurate, and the right amount of fertiliser can be used. All the information gathered by this system would be stored in a safe cloud system which could be used by scientists and farmers to analyse the current status of the soil and take any required measurements.

ON Prime2 Toowoomba teams

Table 8: Toowoomba teams
Team Name Lead Institute Sci-tech proposition

Abalone Waste Utilisation

CSIRO Agriculture

Blacklip abalone, an important part of the Australian seafood industry (worth over $200 million per annum) are generated from 5,000 tonnes of wild-caught and farmed abalone. Abalone is marketed as whole animals, or as processed meat, generating large amounts of waste (shell and offal) which is an environmental and economic problem. Abalone waste has been found to contain bioactive molecules with anti-thrombotic and anti-inflammatory activities. Utilisation of these molecules as ingredients in nutraceuticals and other health products may provide a means to reduce the environmental burden of abalone waste and improve the profit margin in the abalone industry.

Predator Aversion Technologies

University of South Queensland

Livestock producers facing problems with feral pest animals are often unable to control these pests because common control tools place high-value livestock working dogs at great risk of accidental injury and death. There is an urgent need to identify and develop tools that can protect working dogs from poisons, traps and other devices intended to kill pest animals. Development of an autonomous, GPS-enabled aversion collar for livestock working dog owners could eliminate the risk of pest control to working dogs, enable effective pest control programs, and assist the growth of the sheep industry and rural communities.

Real time water quality sensor kit

Water, our most basic need, is poised to be the most baffling challenge of the 21st century. Water contamination restricts urban renewal and other uses and has the potential to negatively impact human and ecosystem health, more than 1 million people per year die from its scarcity and contamination. Thus real-time water quality monitoring of surface water is critical. NanoMat-sense will develop a real-time, fine-scale sensing platform for a broad range of chemical and microbiological contaminants in water. It will be based on advanced functional nano-sensors that can be tailored for high sensitivity and selectivity.

The WiRE (Women in Rural, Regional and Remote Enterprises) Program

University of South Queensland

Women in rural and remote areas face a unique set of challenges when it comes to building their entrepreneurial potential and growing their businesses. We are creating a platform for Women with an entrepreneurial spirit to help build their capabilities so they can take their innovative business ideas to market, scale their existing business, create their social enterprise, and empower their confidence. The programme will deliver measurable increases in women’s entrepreneurial business skills and will create a support ecosystem for rural women entrepreneurs. ‘WiRE’ (Women in Rural Enterprises) is the first major, integrated entrepreneurial capacity building program for Australian Women in Rural Enterprises.

Weed Management System

University of Southern Queensland

Farming systems in Southern Queensland have transformed from regular tillage to zero tillage with a heavy reliance on herbicide. A lack of tillage has favoured weed species e.g. Conyza bonariensis, Sonchus oleraceus, Echinochloa colona. These small-seeded weeds emerge at surface soil when soil moisture and temperature are suitable for their germination. These weeds compete with crops for water and nutrients which consequently reduces crop productivity and profitability. Our solution, WMS (Weed Management System), is a framework which predicts the timing of weed emergence and warns farmers to take a timely action i.e. chemical or non-chemical. This warning system predicts the probability of weed emergence and sends warning emails to the registered farmers and alert them. The system is built by developing a mathematical model based on observations through field experiments.

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